The thinking layer
for fetal ultrasound
ScanOFe™ links abnormal ultrasound findings to malformations, syndromes, genes, and investigations. In real time, without re-interpreting your images.
High-quality imaging.
Overwhelming complexity when findings deviate.
The challenge in fetal medicine is not generating data. It is processing abnormal findings under time pressure, across thousands of overlapping syndromes.
Rare Genetic Disorders
Clinically documented rare genetic conditions, the majority presenting with overlapping prenatal phenotypes that are difficult to distinguish on ultrasound alone.
Source: OMIM Database, 2024Have a Genetic Cause
Of structural fetal anomalies detected on ultrasound have an underlying genetic etiology. Yet many cases receive broad exome sequencing rather than targeted investigation.
Source: ACOG Practice Bulletin No. 162, 2016anomalies
Exponential Diagnostic Complexity
When two or more abnormal findings co-occur, the intersection of possible syndromes becomes unmanageable without structured decision support. Clinicians resort to Google or ChatGPT. Neither built for prenatal phenotyping.
Clinical rationale: Dr. Foram Acharya, 30+ yrs fetal medicineBidirectional intelligence.
Starting from your findings.
ScanOFe never re-interprets your images. It works from the abnormalities you have already identified, then structures the diagnostic thinking that follows.
Abnormal findings in. Ranked differentials out.
Select one or more abnormal ultrasound findings from a structured menu. ScanOFe returns ranked syndrome differentials, associated genes, and targeted investigation recommendations. In seconds.
- 1 Enter findings. Select from structured menus covering all fetal organ systems, or enter biometry measurements
- 2 Centile flagging. Measurements below 5th or above 95th percentile are color-coded automatically against Indian normative data
- 3 Ranked differentials. Possible malformations, syndromes, and associated genes appear ranked by clinical likelihood
- 4 Investigation pathway. Targeted genetic tests recommended with rationale, avoiding unnecessary broad exome sequencing
Built for fetal medicine.
Not adapted from elsewhere.
Clinician-Respecting Design
ScanOFe never re-interprets your images or challenges your findings. It engages only after you have identified an abnormality. Acting as a cognitive partner, not a second-guesser. Expert resistance is the primary reason AI tools fail in clinical adoption; ScanOFe is designed around this reality.
Gestation-Aware Logic
Syndrome phenotypes change across gestational age. A finding significant at 13 weeks may be irrelevant at 24 weeks, and vice versa. ScanOFe weights and filters results by the gestational window of your scan. Not by static reference ranges designed for postnatal presentation.
Indian Normative Data
Biometry centile calculations and Doppler normal ranges are derived from Indian population data. Not Caucasian or Western reference charts that systematically misclassify Indian fetuses. This affects NT, BPD, AC, FL and all Doppler indices.
True Bidirectional Search
Use ScanOFe forward. From findings to syndromes. Or in reverse, from a suspected syndrome to what you should look for on the scan. No other prenatal tool offers both workflows in a single integrated interface.
Platform-Agnostic Access
Cloud-based. Runs on Mac, Windows, or Linux. Available on a tablet beside the ultrasound machine via DICOM transfer, or on a desktop during reporting. No machine-specific installation required.
Gene-Level Linkage
Beyond syndrome identification, ScanOFe links phenotypes directly to causative genes and recommended investigation panels. So the clinical handoff to genetics is structured rather than a referral with no specific test recommendation.
Not a competitor to existing tools.
The missing layer between them.
ScanOFe is complementary to reporting systems like ViewPoint and risk calculators like Astraia. It occupies the decision-support gap that neither addresses.
| Capability | ScanOFe™ | SONIO | GE ViewPoint 6 | Astraia |
|---|---|---|---|---|
| Prenatal-specific syndrome phenotypes | ✓ | ✓ | — | — |
| Works from clinician-entered findings (not images) | ✓ | — | — | — |
| Gestation-aware syndrome weighting | ✓ | Partial | — | — |
| Bidirectional: findings ↔ syndrome | ✓ | — | — | — |
| Gene-level linkage and investigation guidance | ✓ | Partial | — | — |
| Indian population normative data | ✓ | — | — | — |
| First trimester risk calculation (PET, FGR, PTB) | ✓ | — | Partial | ✓ |
| Structured reporting with growth curves | ✓ | — | ✓ | ✓ |
| Cloud-based, platform-agnostic | ✓ | ✓ | — | — |
| ISO 13485 certified QMS | ✓ | ✓ | ✓ | ✓ |
Designed for those who
make the hardest calls.
Fetal Medicine Specialists
You already know what you are looking at. ScanOFe structures the thinking after the abnormality is found. Differential ranking, syndrome phenotyping, genetics pathway. So the cognitive burden of the most complex cases is shared, not dismissed.
- Ranked syndrome differentials when multiple anomalies co-occur
- Reverse phenotype search when a syndrome is suspected from history or NIPT
- Gene-level investigation guidance to avoid blanket exome referrals
- Integrated reporting across FTS, anomaly scan, and third trimester workflows
Radiologists & Advanced Sonographers
When an anomaly scan reveals findings outside your typical reporting scope, ScanOFe provides the structured framework to complete a clinically meaningful report. And clearly communicate what needs follow-up and why.
- Syndrome awareness without fetal medicine subspecialty training
- Structured report templates appropriate to the finding type
- Investigation suggestions to include in referral documentation
- Centile-flagged biometry against Indian population data
Tertiary Fetal Medicine Centres
For centres managing high referral volumes of complex cases, ScanOFe standardizes the decision framework across your team. Reducing variability between consultant and trainee, and creating a documented clinical reasoning trail.
- Consistent decision framework across all team members
- Training tool for registrars and junior consultants
- Audit trail of decision logic for complex cases
- Enterprise licensing with multi-user access
Medical Colleges & Teaching Hospitals
ScanOFe provides structured exposure to rare syndrome phenotypes that a trainee might encounter only a handful of times during residency. Case-based teaching using the decision support interface accelerates pattern recognition.
- Academic licensing at institutional pricing
- Syndrome phenotype library as a structured teaching resource
- CME-compatible case presentation workflows
- NABH-compatible documentation support
Built by clinicians. For clinical reality.
ScanOFe's knowledge base is curated from peer-reviewed medical literature, established prenatal phenotype databases, and over three decades of fetal medicine practice. Not generated algorithmically. Every syndrome entry is reviewed for clinical accuracy before inclusion.
See ScanOFe in your
clinical workflow.
We are onboarding pilot centres. Request a demo and we will schedule a walkthrough with your team. No commitment required.
For institutions and individual clinicians. We will respond within 2 business days.
ScanOFe is a clinical decision support tool. All diagnoses remain the responsibility of the treating clinician.